Colonoscopy Cost in Jacksonville, FL

A colonoscopy is an outpatient procedure in which a clinician guides a flexible, lighted tube with a camera through the colon to capture images of the lining, which are reviewed during the exam and documented in a report. The hospital facility fee generally covers the procedure room, nursing staff, equipment, and supplies, while physician services are billed separately. This page covers two billing codes: 45378 (Screening Colonoscopy) and 45380 (Colonoscopy with Biopsy). Prices come from the price transparency files that CMS requires hospitals to publish, covering 3 hospitals in the Jacksonville area.

Data last accessed by us: 2026-10-15 · Newest hospital file date among hospitals below: 2026-09-01

Incomplete rows: Some hospitals publish $0 / blank amounts for this procedure in their transparency file. Those cells show as N/A and are excluded from the cash range above.

Screening Colonoscopy (HCPCS 45378)

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Hospital Cash Price
HCA Memorial N/A Schedule →
HCA Orange Park N/A Schedule →
UF Health Jacksonville $3,175.77 Schedule →

Colonoscopy with Biopsy (HCPCS 45380)

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Hospital Cash Price
HCA Memorial N/A Schedule →
HCA Orange Park N/A Schedule →
UF Health Jacksonville $3,439.19 Schedule →

What These Prices Mean

Gross charge, cash price and insured range in Jacksonville
The gross charge is a hospital's list price before any discounts. On this page, only UF Health Jacksonville published one: $5,774.13 for 45378 and $6,253.07 for 45380. Its cash prices are $3,175.77 and $3,439.19, which is 55% of gross for both codes. The insured range reflects negotiated rates between the hospital and insurers. At UF Health Jacksonville, the highest insured rates are $5,485.42 for 45378 and $5,940.42 for 45380. People on a high-deductible plan who have not met their deductible usually pay the plan's negotiated rate rather than the gross charge.

How 45378 and 45380 differ
Code 45378 describes a screening colonoscopy, while 45380 describes a colonoscopy with biopsy, meaning tissue samples are taken during the exam. At UF Health Jacksonville, the cash price is $3,175.77 for 45378 and $3,439.19 for 45380. At HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital, insured rates start at $1,226.13 for 45378 and $1,950 for 45380, and both codes reach $14,306 at the top of the range.

Why Colonoscopy Prices Vary

Differences between the three hospitals
The three hospitals belong to two health systems: HCA Healthcare has 2 hospitals on this page and UF Health has 1. Their disclosures look very different. UF Health Jacksonville published both gross charges and cash prices, with cash at 55% of gross. HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital published no cash price for either code, and their gross charges were blank or $0, so those fields are missing data rather than real prices. Cash prices were published in only 2 of 6 rows, and gross charges were missing in 4 rows.

Other facilities and plan-to-plan spread
Outpatient surgery centers and other facilities outside this dataset may price the same procedure differently. The insurer data shows wide variation too. For 45378 at HCA Florida Memorial Hospital, 146 published rates run from $1,226.13 to $14,306, and the highest is about 12x the lowest. Lower entries include workers' compensation rates, while the top entries are Cigna plans.
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Paying cash? Health insurance could lower your Colonoscopy cost.

Published cash prices on this page range from $3,175.77 to $3,439.19. The lowest insured rate in the price table is $1,226.13 (HCA Florida Memorial Hospital). Insured rates depend on the plan, and the lowest are often Medicaid, CHIP or Medicare Advantage plans, so they may not reflect what a commercial or marketplace plan pays. If you are uninsured, a marketplace health plan could reduce your out-of-pocket cost for this procedure.

Links go to Healthcare.gov, the official federal health insurance marketplace. We are not affiliated with Healthcare.gov or any insurance provider. This is not a recommendation for any specific plan.

Compare Insurer Rates for Colonoscopy in Jacksonville

How much does each insurance company pay for colonoscopy at Jacksonville hospitals?

Insurer Lowest Rate Hospitals
Humana $636.88 10
Amerigroup $636.88 6
Simply Healthcare $668.72 9
UnitedHealthcare $700.57 13
AmeriHealth Caritas $700.57 7
Florida Community Care $700.57 7
Sunshine Health $700.57 6
Aetna $704.91 11

Rates shown are the lowest and highest negotiated rates each insurer has published across Jacksonville hospitals for this procedure. Your actual cost depends on your plan's deductible, copay, and coinsurance.

What Insurers Actually Pay

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Published negotiated rates for Screening Colonoscopy (HCPCS 45378) at HCA Memorial, outpatient facility fee:

Screening Colonoscopy (45378), HCA Memorial Payer Rates

Insurance Payer Plan Type Negotiated Rate
City of Jacksonville WC $1,226.13
CorVel Corporation WORKERSCOMP $1,226.13
Prime Health WORKERSCOMP $1,251.94
Optimum Healthcare MGMCR $1,950
Optimum Healthcare MGMCR $1,950
Optimum Healthcare MGMCR $1,950
Optimum Healthcare MGMCR $1,950
City of Jacksonville WC $1,994.26
CorVel Corporation WORKERSCOMP $1,994.26
Prime Health WORKERSCOMP $2,036.24
Simply Healthcare MGMCR $2,250
Simply Healthcare MGMCR $2,250
Simply Healthcare MGMCR $2,250
Simply Healthcare MGMCR $2,250
Positive Healthcare MCR $2,450
Positive Healthcare MCR $2,450
Positive Healthcare MCR $2,450
Positive Healthcare MCR $2,450
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
BCBS MBN $2,633
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Molina Healthcare HIX $2,702
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
Simply Healthcare HIX $2,735
BCBS BSLNON-PAR $3,238
BCBS PHS $3,238
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
BCBS HMO $3,278
BCBS SBN $3,278
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
Oscar HIX $3,390
BCBS NWB $4,101
BCBS PPO $4,101
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
United AllPayerAppendix $4,750
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Corizon COMM $5,516
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Centurion PRISN $7,512
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna NBN $10,835
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306
Cigna OAP $14,306
Cigna PPO $14,306

Key finding: For 45378 at HCA Florida Memorial Hospital, Cigna OAP and PPO rates of $14,306 are about 12x the lowest published rate of $1,226.13, listed for City of Jacksonville and CorVel Corporation.

What to Do With These Colonoscopy Prices

Call with two billing codes, then ask about biopsy. Ask each hospital for its cash or self-pay price and an itemized estimate under 45378 (screening) and 45380 (colonoscopy with biopsy). A biopsy can be decided only during the procedure, so a quote for both codes shows the range. You can also ask your insurer how a biopsy changes your share of the cost.

Measure any quote against the numbers on this page. On this page, UF Health Jacksonville is the only hospital with published cash prices: $3,175.77 for 45378 and $3,439.19 for 45380. Its insured rates top out at $5,485.42 for 45378, so a cash quote sits below that ceiling at this hospital. Insured rates at HCA Florida Orange Park Hospital reach as high as $14,306, so the spread between hospitals is wide. If your insurer is on the page, compare your quote with its listed range.

Sort the bills by who sent them. The hospital's facility fee covers the room, equipment and nursing. Separate bills commonly arrive from:

  • the gastroenterologist who performs the procedure
  • the anesthesia provider
  • the pathology lab, if tissue is sent for testing

Check each bill against your estimate, and ask the hospital which of these providers bill separately.

Blanks mean missing, not free. Of the 6 price rows here, 4 have a gross charge published as $0 or blank, and HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital show no cash price. That is missing data, so call them directly for a quote.

Financial assistance and discounts. Nonprofit hospitals are required to publish a financial assistance policy, and the billing office can send it with an application. Some hospitals also offer prompt-pay or self-pay discounts; these vary by hospital and are not included in this data. If you are uninsured or not using insurance for scheduled care, you can ask the provider for a good faith estimate before the appointment.

General information about using published prices, not medical, legal or financial advice. Confirm your own cost with the hospital and your insurer. Our methodology · Medical Disclaimer

What Patients Ask About Colonoscopy Costs

How much does a colonoscopy cost without insurance in Jacksonville?

Based on published cash prices, a colonoscopy at UF Health Jacksonville is $3,175.77 for code 45378 (Screening Colonoscopy) and $3,439.19 for code 45380 (Colonoscopy with Biopsy). Those are the only cash prices on this page. HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital did not publish a cash price for either code, so that data is missing and no self-pay figure can be shown for them. These amounts are facility charges only. Professional fees, such as the physician's services and anesthesia, are billed separately and are not included.

Why is the gross charge so much higher than the cash price?

The gross charge is a list price that hospitals set before discounts, and few patients pay it. At UF Health Jacksonville, the gross charge is $5,774.13 for 45378 and $6,253.07 for 45380, while the published cash prices are $3,175.77 and $3,439.19. In both cases, the cash price is 55% of gross. The other two hospitals on this page, HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital, published gross charges that were blank or $0, so no comparison with a cash price is possible for them.

Does insurance cover a colonoscopy?

Whether insurance covers a colonoscopy depends on your specific plan, so the plan itself or the insurer is the source for coverage details. The hospital files show negotiated rates for all 3 hospitals on this page. At UF Health Jacksonville, the highest insured rates are $5,485.42 for 45378 and $5,940.42 for 45380. At HCA Florida Memorial Hospital, rates for 45378 range from $1,226.13 to $14,306. If you have a high-deductible plan and have not met your deductible, you usually pay the plan's negotiated rate until it is met.

Are there additional fees beyond the colonoscopy facility charge?

Yes. The facility charge on this page covers the hospital's side of the procedure only. Separate bills commonly come from the physician who performs the exam, the anesthesia provider, and a pathology laboratory if tissue samples are examined. Some patients also receive separate charges for a facility-based professional reading of results or for follow-up care. These providers may bill independently and may or may not be in your insurer's network, so itemized statements are useful for seeing what each bill covers.

What is the cash price for a colonoscopy at UF Health Jacksonville?

UF Health Jacksonville publishes a cash price of $3,175.77 for Screening Colonoscopy (45378) and $3,439.19 for Colonoscopy with Biopsy (45380). Both are facility charges only, and the page shows each cash price as 55% of the gross charge. Professional fees are not included in these figures.

Do HCA Florida Memorial Hospital and HCA Florida Orange Park Hospital list cash prices for colonoscopy?

No. Neither HCA Florida Memorial Hospital nor HCA Florida Orange Park Hospital has a published cash price for 45378 or 45380 on this page. Their gross charges are also missing, shown as $0 or blank in the source data. Missing means the figure was not published, not that the procedure is free.

What are the lowest and highest cash prices for a colonoscopy in Jacksonville?

Among the cash prices published for Jacksonville, the lowest is $3,175.77 for Screening Colonoscopy (45378) at UF Health Jacksonville and the highest is $3,439.19 for Colonoscopy with Biopsy (45380) at UF Health Jacksonville. Only 2 of the 6 price rows include a cash price, and these are facility charges only.

What is the difference between CPT 45378 and 45380 prices in Jacksonville?

Code 45378 is Screening Colonoscopy and 45380 is Colonoscopy with Biopsy. At UF Health Jacksonville, the gross charge is $5,774.13 for 45378 and $6,253.07 for 45380, and the cash prices are $3,175.77 and $3,439.19. These are facility charges only.

Compare Other Procedures in Jacksonville

Data Sources

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Heads up: source files are large

Hospital CMS transparency files typically range from tens of megabytes to several hundred megabytes. Clicking a link below will open the file in a new tab and may trigger a large download, which can consume mobile data or slow down older devices. These files are intended for data processing, not casual viewing.

Ascension St. Vincent's Clay County

File updated: 01/01/2026 · Accessed by us: 2026-10-15

Attested by: Bryan Walrath

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Ascension St. Vincent's Riverside

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Attested by: Scott Kashman

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Ascension St. Vincent's Southside

File updated: 01/01/2026 · Accessed by us: 2026-10-15

Attested by: Susan Cornejo

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Ascension St. Vincent's St. Johns County

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Attested by: Cory Darling

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Baptist Medical Center Beaches

File updated: 2026-02-06 · Accessed by us: 2026-10-15

Attested by: Matthew Zuino

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Baptist Medical Center Clay

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Baptist Medical Center Jacksonville

File updated: 2026-02-06 · Accessed by us: 2026-10-15

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Baptist Medical Center Nassau

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Baptist Medical Center South

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Wolfson Children's Hospital

File updated: 2026-02-06 · Accessed by us: 2026-10-15

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HCA Florida Memorial Hospital

File updated: 2026-09-01 · Accessed by us: 2026-10-15

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HCA Florida Orange Park Hospital

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UF Health Jacksonville

File updated: 2026-03-31 · Accessed by us: 2026-10-15

Attested by: Kent Bailey

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