Colonoscopy Cost in Knoxville, TN

A colonoscopy is an outpatient procedure in which a physician guides a flexible, lighted tube with a camera through the colon to view its lining on a screen. The procedure produces video images and, when tissue samples are taken, specimens sent to a laboratory for results. The hospital facility fee covers the procedure room, nursing staff, equipment and supplies, but not the physician's own services. This page covers two billing codes: 45378 for screening colonoscopy and 45380 for colonoscopy with biopsy. All prices come from the price transparency files that CMS requires hospitals to publish, covering 9 hospitals in the Knoxville area.

Data last accessed by us: 2026-10-15 · Newest hospital file date among hospitals below: 2026-08-27

Incomplete rows: Some hospitals publish $0 / blank amounts for this procedure in their transparency file. Those cells show as N/A and are excluded from the cash range above.

Screening Colonoscopy (HCPCS 45378)

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Hospital Cash Price
Fort Loudoun N/A Schedule →
Fort Sanders Regional N/A Schedule →
Methodist Oak Ridge N/A Schedule →
Parkwest N/A Schedule →
Roane Medical Center N/A Schedule →
LaFollette Medical Center $3,865.88 Schedule →
Tennova North Knoxville $3,177.80 Schedule →
Tennova Turkey Creek $2,678.32 Schedule →
UT Medical Center $543.50 Schedule →

Colonoscopy with Biopsy (HCPCS 45380)

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Hospital Cash Price
Fort Loudoun N/A Schedule →
Fort Sanders Regional N/A Schedule →
Methodist Oak Ridge N/A Schedule →
Parkwest N/A Schedule →
Roane Medical Center N/A Schedule →
LaFollette Medical Center $4,326 Schedule →
Tennova North Knoxville $3,783.61 Schedule →
Tennova Turkey Creek $3,592.80 Schedule →
UT Medical Center $489.25 Schedule →

What These Prices Mean

Gross, cash and insured figures on this page
The gross charge is a hospital's full list price before any discounts. The cash price is the amount offered to people paying without insurance. Insured rates are the negotiated amounts that health plans pay. Among the 8 of 18 rows with a published cash price, cash is 27% of gross at LaFollette Medical Center, 23% at Tennova North Knoxville Medical Center, 22% at Tennova Turkey Creek Medical Center and 25% at The University of Tennessee Medical Center. Gross charges run from $1,957 at The University of Tennessee Medical Center (45380) to $16,704.66 at Tennova North Knoxville Medical Center (45380). People on a high-deductible plan who have not yet met their deductible usually pay the plan's negotiated rate, not the gross charge.

Screening versus biopsy codes
Code 45378 covers a screening colonoscopy, while 45380 covers a colonoscopy in which a biopsy is taken. At LaFollette Medical Center the cash price is $3,865.88 for 45378 and $4,326 for 45380. At Tennova Turkey Creek Medical Center it is $2,678.32 for 45378 and $3,592.80 for 45380. At The University of Tennessee Medical Center the listing runs the other way, with $543.50 for 45378 and $489.25 for 45380.

Why Colonoscopy Prices Vary

Differences between systems
The three systems on this page publish very different figures. Covenant Health has 5 hospitals here, and none of them lists a gross charge or a cash price for either code, so those fields count as missing data. Tennova Healthcare has 3 hospitals, with cash prices from $2,678.32 to $4,326 and gross charges from $12,308.45 to $16,704.66. The University of Tennessee Medical Center is the only hospital in its system on this page, with cash prices of $489.25 and $543.50. Across all published cash prices, the highest is about 9x the lowest, and the same holds for gross charges. Cash discounts range from 22% to 27% of gross among hospitals that publish both.

Beyond hospital outpatient departments
Ambulatory surgery centers and physician-owned endoscopy suites are outside this dataset and may price the same procedure differently. Plan-to-plan variation is also wide. For code 45380 at The University of Tennessee Medical Center, 211 published rates run from $182.95 for an Aetna Medicare Advantage plan to $1,957 for Prime Health workers compensation entries. The highest is about 11x the lowest in that table.
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Paying cash? Health insurance could lower your Colonoscopy cost.

Published cash prices on this page range from $489.25 to $4,326. The lowest insured rate in the price table is $84.33 (The University of Tennessee Medical Center). Insured rates depend on the plan, and the lowest are often Medicaid, CHIP or Medicare Advantage plans, so they may not reflect what a commercial or marketplace plan pays. If you are uninsured, a marketplace health plan could reduce your out-of-pocket cost for this procedure.

Links go to Healthcare.gov, the official federal health insurance marketplace. We are not affiliated with Healthcare.gov or any insurance provider. This is not a recommendation for any specific plan.

Compare Insurer Rates for Colonoscopy in Knoxville

How much does each insurance company pay for colonoscopy at Knoxville hospitals?

Insurer Lowest Rate Hospitals
Aetna $84.33 9
BlueCross BlueShield of Tennessee $84.61 9
Humana $84.61 9
UnitedHealthcare $84.61 9
Cigna $85.16 9
Amerigroup $87.14 9
BlueCare Tennessee $371.49 4
MultiPlan/PHCS $612.87 4

Rates shown are the lowest and highest negotiated rates each insurer has published across Knoxville hospitals for this procedure. Your actual cost depends on your plan's deductible, copay, and coinsurance.

What Insurers Actually Pay

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Published negotiated rates for Colonoscopy with Biopsy (HCPCS 45380) at UT Medical Center, outpatient facility fee:

Colonoscopy with Biopsy (45380), UT Medical Center Payer Rates

Insurance Payer Plan Type Negotiated Rate
Aetna Medicare Advantage $182.95
Blue Cross Medicare Advantage $183.74
Humana MedAdv HMO,POS,PPO $183.74
NHC Medicare Advantage $183.74
UHC VACCN $183.74
Cigna Medicare Advantage $184.74
American Health MedAdv HMO ISNP $188.33
Cigna Commercial LCP $208.32
Blue Cross BCBS Network L $255.96
NX Health 1 Commercial $282.78
Blue Cross BCBS Network S $287.46
Blue Cross BCBS Network P $318.96
Cigna Commercial OAP $320.49
Blue Cross CoverKids PCP $322.30
Blue Cross CoverKids Special $322.30
Blue Cross CoverKids PCP $322.30
Blue Cross CoverKids Special $322.30
ChoiceCare Commercial $328.45
United HealthCare UHC Community TennCare $346.50
Aetna Commercial $357.46
BlueCare PCP $371.49
BlueCare PCP $371.49
Aetna Medicare Advantage $385.74
Cigna Medicare Advantage $389.53
Blue Cross Medicare Advantage $394.60
ChoiceCare MA PPO $394.60
Humana MedAdv HMO,POS,PPO $394.60
NHC Medicare Advantage $394.60
UHC VACCN $394.60
BlueCare Special $395.03
TennCare Select $395.03
BlueCare Special $395.03
TennCare Select $395.03
American Health MedAdv HMO ISNP $397.09
Humana MedAdv HMO,POS,PPO $416.34
NovaNet Commercial $451.78
Cigna Commercial LCP $462.09
Blue Cross BCBS Network L $491.09
Blue Cross BCBS Network S $551.53
ChoiceCare Commercial $586.28
Initial Group Commercial $611.88
Blue Cross BCBS Network P $611.97
Coventry HMO/POS/PPO $612.87
MultiPlan Commercial $612.87
MultiPlan Commercial $612.87
First Health Commercial $674.16
Cigna Commercial OAP $710.91
Beechstreet Commercial $711.90
Beechstreet Commercial $711.90
Blue Cross TennCare Select $777
Aetna Commercial $781
NovaNet Commercial $782.32
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Fentress County Sheriffs Dept Fentress County Inmates $782.80
Aetna Commercial $790.44
Wellpoint TNCare $808.78
Cigna IFP Connect $823.90
Cigna Local Plus $823.90
Cigna IFP Connect $823.90
Cigna Local Plus $823.90
Cigna IFP Connect $823.90
Cigna Local Plus $823.90
Cigna IFP Connect $850
Cigna Local Plus $875
United HealthCare Commercial $880.65
United HealthCare Core $880.65
United HealthCare Heritage Select $880.65
United HealthCare Nexus ACO OAP $880.65
United HealthCare Tn Individual Exchange Benefit $880.65
United HealthCare Commercial $880.65
United HealthCare Core $880.65
United HealthCare Heritage Select $880.65
United HealthCare Nexus ACO OAP $880.65
United HealthCare Tn Individual Exchange Benefit $880.65
United HealthCare Commercial $880.65
United HealthCare Core $880.65
United HealthCare Heritage Select $880.65
United HealthCare Nexus ACO OAP $880.65
United HealthCare Tn Individual Exchange Benefit $880.65
Blue Cross BlueCare TennCare $908.26
Blue Cross CoverKids TennCare $908.26
Optum/UHC Kidney Transplant Tenncare $915.15
Blue Cross BCBS Network E $1,037.21
Blue Cross BCBS Network L $1,037.21
Blue Cross BCBS Network E $1,037.21
Blue Cross BCBS Network L $1,037.21
Blue Cross BCBS Network E $1,037.21
Blue Cross BCBS Network L $1,037.21
Cigna Cigna HealthSpring MedAdv $1,076.64
Humana Choice MedAdv PPO $1,076.64
Humana Humana Medicare $1,076.64
Humana MedAdv HMO,POS,PPO $1,076.64
Humana MedAdv HVN $1,076.64
Optum/UHC Kidney Transplant Medicare $1,076.64
United HealthCare MedAdv/AARP $1,076.64
United HealthCare UHC Community D-SNP $1,076.64
United Optum VACCN United Optum VACCN $1,076.64
United Optum VACCN VACCN Transplant $1,076.64
Wellpoint MedAdv DSNP $1,088.28
United HealthCare Commercial $1,093
United HealthCare Core $1,093
United HealthCare Heritage Select $1,093
United HealthCare Nexus ACO OAP $1,093
Blue Cross MedAdv D-SNP $1,108.94
Aetna MedAdv PPO $1,119.71
Devoted Health MedAdv $1,119.71
Blue Cross MedAdv PPO $1,130.48
Wellcare-Windsor MedAdv MedAdv $1,130.48
Aetna Commercial $1,131.15
Aetna Commercial $1,131.15
Aetna Commercial $1,131.15
Blue Cross BCBS Network E $1,134
Blue Cross BCBS Network L $1,134
Blue Cross BCBS Network S $1,135.06
Blue Cross BCBS Network S $1,135.06
Blue Cross BCBS Network S $1,135.06
American Health MedAdv HMO ISNP $1,141.24
NHC MedAdv ISNP $1,141.24
Signature Medicare Advantage MedAdv ISNP $1,141.24
Wellpoint MedAdv $1,141.24
Sterling Advantage Medicare MedAdv PPO $1,152.01
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
MultiPlan Commercial $1,174.20
NX Health Commercial $1,174.20
PHCS Commercial $1,174.20
Blue Cross BCBS Network P $1,252.48
Blue Cross BCBS Network P $1,252.48
Blue Cross BCBS Network P $1,252.48
Blue Cross BCBS Network S $1,270
NaphCare McCreary County USP $1,272.05
NaphCare McCreary County USP $1,272.05
NaphCare McCreary County USP $1,272.05
NaphCare McCreary County USP $1,272.05
NaphCare McCreary County USP $1,272.05
NaphCare McCreary County USP $1,272.05
United HealthCare Tn Individual Exchange Benefit $1,365
Aetna First Health Network $1,369.90
Aetna First Health Network $1,369.90
Aetna First Health Network $1,369.90
Aetna First Health Network $1,369.90
Coventry HMO/POS/PPO $1,369.90
Optum/UHC Kidney Transplant Commercial $1,369.90
Aetna First Health Network $1,369.90
Coventry HMO/POS/PPO $1,369.90
Optum/UHC Kidney Transplant Commercial $1,369.90
Aetna First Health Network $1,369.90
Coventry HMO/POS/PPO $1,369.90
Optum/UHC Kidney Transplant Commercial $1,369.90
Blue Cross BCBS Network P $1,428
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Beechstreet Commercial $1,467.75
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Beechstreet Commercial $1,467.75
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Beechstreet Commercial $1,467.75
Prime Health PPO $1,467.75
Seven Corners McCreary County USP $1,467.75
Cigna HMO/NL/OAP/Other/GW $1,485.36
Cigna HMO/NL/OAP/Other/GW $1,485.36
Cigna HMO/NL/OAP/Other/GW $1,485.36
USA MCO EPO $1,565.60
USA MCO PPO $1,565.60
USA MCO EPO $1,565.60
USA MCO PPO $1,565.60
USA MCO EPO $1,565.60
USA MCO PPO $1,565.60
Cigna HMO/NL/OAP/Other/GW $1,666
Coventry HMO/POS/PPO $1,750
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Evolutions Commercial $1,761.30
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Evolutions Commercial $1,761.30
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Evolutions Commercial $1,761.30
Galaxy Commercial $1,761.30
HealthSmart Commercial $1,761.30
Prime Health Workers Comp $1,957
Prime Health Workers Comp $1,957
Prime Health Workers Comp $1,957

Key finding: At The University of Tennessee Medical Center, the 45380 rate is $182.95 for Aetna Medicare Advantage and $1,957 for Prime Health workers compensation, about 11x higher.

What to Do With These Colonoscopy Prices

Quote both codes when you call. Give the billing office 45378 (screening colonoscopy) and 45380 (colonoscopy with biopsy). A biopsy can only be decided during the procedure, so ask for a cash or self-pay quote and an itemized estimate covering both codes. Then ask your insurer how a biopsy changes your share compared with a screening-only visit.

Line up the quote against this page. On this page, published cash prices run from $489.25 at The University of Tennessee Medical Center (45380) to $4,326 at LaFollette Medical Center (45380). Note that no hospital here has a cash price below every insured rate or above every insured rate, so a cash quote is not automatically the lower or higher option. Compare it with the insured range for the same hospital and code, such as $843.73 to $2,945 listed for 45378 at Fort Loudoun Medical Center, and with what your own plan says you would owe.

Expect more than one bill. The prices above are facility charges only. Check the itemized bill for:

  • The facility fee from the hospital or endoscopy center.
  • The gastroenterologist's professional fee.
  • A separate anesthesia bill, if sedation was given.
  • A pathology lab bill, if tissue was sent for testing.

Ask whether the quote includes each of these or only the facility portion, and whether each provider is in your network.

Blanks are not free. Cash prices are missing for 10 of the 18 rows, and five hospitals publish no cash price for either code. A $0 or blank entry means the hospital did not publish a figure, not that the service costs nothing. Call those hospitals directly for a quote.

Financial assistance and discounts. Nonprofit hospitals are required to publish a financial assistance policy, and the billing office can send it with an application. Some hospitals also offer prompt-pay or self-pay discounts; these vary by hospital and are not included in this data. If you are uninsured or not using insurance for scheduled care, you can ask the provider for a good faith estimate before the appointment.

General information about using published prices, not medical, legal or financial advice. Confirm your own cost with the hospital and your insurer. Our methodology · Medical Disclaimer

What Patients Ask About Colonoscopy Costs

How much does a colonoscopy cost without insurance in Knoxville?

Among published cash prices on this page, a colonoscopy facility fee runs from $489.25 at The University of Tennessee Medical Center (45380) to $4,326 at LaFollette Medical Center (45380). Tennova North Knoxville Medical Center and Tennova Turkey Creek Medical Center also publish cash prices. Five hospitals list no cash price for either code: Fort Loudoun Medical Center, Fort Sanders Regional Medical Center, Methodist Medical Center of Oak Ridge, Parkwest Medical Center and Roane Medical Center. That is missing data, not a price of zero. These figures cover the facility charge only. Professional fees, such as the physician's services, are billed separately.

Why is the gross charge so much higher than the cash price?

The gross charge is the hospital's full list price, and few patients pay it. Cash prices are set as a discounted share of that list price. On this page, cash is 27% of gross at LaFollette Medical Center, 23% at Tennova North Knoxville Medical Center, 22% at Tennova Turkey Creek Medical Center and 25% at The University of Tennessee Medical Center. For example, LaFollette Medical Center lists a gross charge of $16,022.22 for 45380 against a cash price of $4,326. Ten of the 18 rows have no gross charge published, so no comparison is possible for those hospitals.

Does insurance cover a colonoscopy?

Whether a colonoscopy is covered depends on the specific plan, so the plan itself or the insurer is the source for that answer. This page shows negotiated rates for all 9 hospitals. Insured rates range from $84.33 at The University of Tennessee Medical Center (45378) to $181,550.16 at LaFollette Medical Center (45380). At The University of Tennessee Medical Center, 211 published rates for 45380 range from $182.95 to $1,957. If you are on a high-deductible plan and have not met your deductible, you usually pay the plan's negotiated rate for the facility charge.

Are there additional fees beyond the colonoscopy facility charge?

Yes. The facility charge is only one part of the total. A colonoscopy typically also generates a separate bill from the physician who performs it. An anesthesia provider or group often bills separately for sedation. If tissue samples are taken, a pathology laboratory usually bills separately for analyzing them. Some patients also receive separate charges for supplies, medications or bowel preparation. Each of these bills may come from a different provider, and each may be handled differently by an insurance plan. An itemized statement and the insurer's explanation of benefits show which charges were billed.

What is the cash price for a colonoscopy at The University of Tennessee Medical Center in Knoxville?

The University of Tennessee Medical Center publishes a cash price of $543.50 for 45378 (Screening Colonoscopy) and $489.25 for 45380 (Colonoscopy with Biopsy). Both are facility charges only, so professional and other separate fees are not included. Its gross charges for the same codes are $2,174 and $1,957.

What is the highest published cash price for a colonoscopy in Knoxville?

The highest cash price on this page is $4,326 at LaFollette Medical Center for 45380 (Colonoscopy with Biopsy). This is a facility charge only. The lowest cash price shown is $489.25 at The University of Tennessee Medical Center for the same code, and the highest is about 9x the lowest.

Why do some Knoxville hospitals show no cash price for colonoscopy?

Five of the 9 hospitals on this page have no published cash price for either code: Fort Loudoun Medical Center, Fort Sanders Regional Medical Center, Methodist Medical Center of Oak Ridge, Parkwest Medical Center and Roane Medical Center. Blank or $0 entries mean the data is missing, not that the procedure is free.

What does Aetna pay for a colonoscopy with biopsy at The University of Tennessee Medical Center?

Aetna's Medicare Advantage rate for 45380 (Colonoscopy with Biopsy) at The University of Tennessee Medical Center is $182.95, the lowest of the 211 published rates for that code. This is a facility charge only. Other payers in the table, such as HealthSmart at $1,761.30, show higher rates.

How wide is the range of insured rates for colonoscopy at LaFollette Medical Center?

For 45380 (Colonoscopy with Biopsy), LaFollette Medical Center lists insured rates from $378.18 to $181,550.16, the highest insured rate on this page. For 45378 (Screening Colonoscopy) the range is from $299.66 to $141,089.85. These are facility charges only.

Compare Other Procedures in Knoxville

Data Sources

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Heads up: source files are large

Hospital CMS transparency files typically range from tens of megabytes to several hundred megabytes. Clicking a link below will open the file in a new tab and may trigger a large download, which can consume mobile data or slow down older devices. These files are intended for data processing, not casual viewing.

Fort Loudoun Medical Center

File updated: 2026-08-27 · Accessed by us: 2026-10-15

Attested by: Robert Boos

We are not affiliated with Fort Loudoun Medical Center. Published prices may not reflect your actual cost. Disclaimer

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Fort Sanders Regional Medical Center

File updated: 2026-08-05 · Accessed by us: 2026-10-15

Attested by: Robert Boos

We are not affiliated with Fort Sanders Regional Medical Center. Published prices may not reflect your actual cost. Disclaimer

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Methodist Medical Center of Oak Ridge

File updated: 2026-08-05 · Accessed by us: 2026-10-15

Attested by: Robert Boos

We are not affiliated with Methodist Medical Center of Oak Ridge. Published prices may not reflect your actual cost. Disclaimer

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Parkwest Medical Center

File updated: 2026-08-05 · Accessed by us: 2026-10-15

Attested by: Robert Boos

We are not affiliated with Parkwest Medical Center. Published prices may not reflect your actual cost. Disclaimer

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Roane Medical Center

File updated: 2026-08-05 · Accessed by us: 2026-10-15

Attested by: Robert Boos

We are not affiliated with Roane Medical Center. Published prices may not reflect your actual cost. Disclaimer

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LaFollette Medical Center

File updated: 2026-04-01 · Accessed by us: 2026-10-15

Attested by: Tony Benton

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Tennova North Knoxville Medical Center

File updated: 2026-04-01 · Accessed by us: 2026-10-15

Attested by: Tony Benton

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Tennova Turkey Creek Medical Center

File updated: 2026-04-01 · Accessed by us: 2026-10-15

Attested by: Tony Benton

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The University of Tennessee Medical Center

File updated: 1/1/2026 · Accessed by us: 2026-10-15

Attested by: Roger Massey

We are not affiliated with The University of Tennessee Medical Center. Published prices may not reflect your actual cost. Disclaimer

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